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Two old dermal fibroblast lines from individuals over 80 years old (3-OM & 4-OF) and two young skin fibroblast lines from individuals below 30 years old (1-YM & 2-YF) were selected for MB treatment (Supplemental Table 1)

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TMAO has been implicated in the development and progression of chronic inflammatory diseases, including atherosclerosis, chronic kidney disease, obesity, non-alcoholic fatty liver disease (NAFLD), Alzheimers disease and cancer [2, 1216]

In cI, cleavage of NDUFS1 by caspase-3 inhibits cI activities, causing ROS production and collapse of mitochondria membrane potential

Berlin, Heidelberg: Springer

BP, a commonly used apitherapeutic, varies in chemical composition depending on geographic origin, plant source, soil type, bee race, activities, and climatic conditions (8, 11, 30, 46, 81)