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[11] TMG can help replenish methyl groups and facilitate the clearance of nicotinamide, theoretically reducing the buildup of by-products that could cause fatigue or headaches in some individuals

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10.1016/j.bbrc.2009.09.018 164 TanS

Similarly, secretin, although less studied for weight loss, regulates digestion, fat absorption and digestion, that may provide broader benefits for metabolic therapies

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