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Stimulatory signals: GHRH from hypothalamus (primary stimulator), ghrelin from stomach, deep sleep, exercise, fasting/low blood glucose, certain amino acids

IGF-1 LR3 AND IGF DES 1,3 EFFECTS Effects of IGF-1 LR3 The effects of IGF-1 LR3 and IGF DES 1,3 are different due to their structural variations and half-lives