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Research published in the Journal of Biological Chemistry has confirmed that the copper-peptide complex maintains stability across physiological pH ranges (6.5-7.5), resisting dissociation under normal tissue conditions

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A nationwide, population-based cohort study carried out in Denmark including 155 patients with PWS that were followed-up from birth through to first occurrence of an outcome of interest found an increased risk of myocardial infarction, deep venous thrombosis and pulmonary embolisms in these subjects compared to a matched population cohort [32]

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