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Low vitamin B 12 intake during pregnancy and lactation and low breastmilk vitamin 12 content in rural Kenyan women consuming predominantly maize diets

doi: 10.1038/ni.3577 50 ByersdorferCATkachevVOpipariAWGoodellSSwansonJSandquistSet al

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Off-label use means the medication is being used in a manner not specifically approved by the FDA.

Functionally it is a straightforward GHRH-receptor agonist: it binds the receptor on pituitary somatotrophs and stimulates endogenous, pulsatile GH release, which secondarily raises IGF-1