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The medications investigated for CHAC1 targeting include natural products, synthetic derivatives, traditional Chinese medicine, and common pharmaceuticals like metformin

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Exposure to heated tobacco products aerosol causes acute stress responses in the lung of mouse

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In studies involving the IMQ mouse model, a marked elevation of Tbxar2 mRNA expression has been observed in V4+ T cells, which facilitates the enhanced secretion of IL-17A in these T cells, ultimately contributing to the manifestation of skin lesions reminiscent of psoriasis