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For the core programme (without medication), independent research published in The Lancet found that WeightWatchers participants lost around 2.6kg more than a self-directed group at 12 months

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Of note a Mendelian randomization study did not demonstrate a causal role of total cholesterol, LDL cholesterol, HDL cholesterol, or triglycerides on DR (61)

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A prescription from a healthcare provider is often required