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IKK activity is triggered during aging by NF-B (Kim et al., 2002), which further modulates the p38 MAPK, extracellular signal-regulated kinase (ERK), and c-Jun N-terminal kinases (JNKs) pathways that modulate the NF-B-dependent transcriptional activity during the inflammatory reaction

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doi: 10.3389/fmed.2025.1594702 Received 16 March 2025 Accepted 27 August 2025 Published 10 September 2025 Volume 12 - 2025 Edited by Etienne Marbaix, Universit Catholique de Louvain, Belgium Reviewed by Andrei Adrian Tica, University of Medicine and Pharmacy of Craiova, Romania Ramiro Cabrera Carranco, Instituto Doyenne, Mexico Updates Copyright 2025 Gao and Du

Childrens doses are scaled to weight (0.020.3 mg/kg/day)

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