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Mechanism of Action Sermorelin exerts its effects through high-affinity binding to and activation of growth hormone-releasing hormone receptors (GHRHR) expressed on somatotroph cells in the anterior pituitary gland

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Our previous studies revealed the essential role of HGF in mechano-biology of postnatal muscle growth and regeneration centered on resident myogenic stem satellite cells, which are positioned between the basal lamina and the sarcolemma of postnatal myofibers and normally found in a mitotically and metabolically quiescent or near-dormant state (protracted G 1 phase, also referred to G 0 ) in adult muscle

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