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Mucin degrader Akkermansia muciniphila accelerates intestinal stem cell-mediated epithelial development

Drug metabolism was affected by nutritional status as the glucuronidation reaction rate changed

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Intravenous administration revealed distinct pharmacokinetic characteristics: serum analysis demonstrated 94% molecular integrity of FGF-21 at 10 min post-infusion, while intracerebral measurements showed 75% preservation of intact molecules

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