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Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and S(N)1 chemotherapeutic agents

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Other antioxidant strategies, such as N-acetylcysteine (NAC), have also been investigated as ways to support glutathione production and reduce oxidative stress

Advances in nanotechnology have also improved flavonoid delivery to melanoma cells, enhancing their stability and effectiveness in preclinical models, though regulatory challenges remain for clinical applications 148

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Tam S, Amit M, Boonsripitayanon M, Busaidy NL, Cabanillas ME, Waguespack SG, Gross ND, Grubbs EG, Williams MD, Lai SY, Sturgis EM, Zafereo ME