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One of the major contributors in the inflammatory cascades is the high mobility group box 1 protein (HMGB1), which is overexpressed during neuroinflammation

IGF-1LR3 (Insulin-like Growth Factor-1 Long Arg3) je modifikovan peptid odvozen z pirozenho inzulnu podobnho rstovho faktoru IGF-1. Jeho hlavn charakteristikou je prodlouen doba inku ve srovnn se standardn formou IGF-1, a to dky strukturln zmn, pi n arginin nahrazuje glutamin na tet pozici aminokyselinovho etzce

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reported that the system Xc inhibitor erastin and the GPX4 inhibitor RSL3 increased the susceptibility of lens epithelial cells to ferroptosis (329)