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doi:10.1038/jhg.2010.53

Upon reaching the liver, these toxic compounds can overwhelm phase I and phase II detoxification pathways (174)

The complications of Genital Melanotic Macules may include the following: The longstanding skin patches can cause emotional stress and cosmetic concerns in some individuals The appearance of the pigmented macules may induce a fear of melanoma (which is a type of skin cancer) Complications that arise from an underlying genetic condition/syndrome How is Genital Melanotic Macules Treated

J Inherit Metab Dis 34:1732 Stipanuk MH, Coloso RM, Garcia RAG, Banks MF (1992) Cysteine concentration regulates cysteine metabolism to glutathione, sulfate and taurine in rat hepatocytes

Together, these findings demonstrate that targeted liposomal delivery enables more effective treatment of pancreatic cancer