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10.1038/s41574-022-00757-5 22
This metabolic boost helps: Break through weight loss plateaus Accelerate fat loss Improve energy expenditure in individuals with sluggish metabolism This is achieved through beta-3 adrenergic receptor activation in fat cells, which increases lipolysisthe breakdown of fat into usable energy substrates 3
doi: 10.1111/apm.13159 29
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Key Highlights from REIMAGINE 13 REIMAGINE 1 (Diet & Exercise Alone) 40 Weeks HbA1c reduction: 1.8% Weight loss: 13.8% Baseline HbA1c: 7.8% REIMAGINE 2 (Metformin SGLT2 Inhibitor) 68 Weeks HbA1c reduction: 1.91% Weight loss: 14.2% Demonstrated superiority over semaglutide 2.4 mg: * HbA1c: 1.91% vs 1.75% * Weight loss: 14.2% vs 10.2% REIMAGINE 3 (Add-on to Basal Insulin) 40 Weeks HbA1c reduction: 2.33% Weight loss: 12.0% Achieved meaningful metabolic improvements despite background insulin therapy
Youre under chronic stress : High stress levels can make your symptoms more intense and more frequent
