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Investigating the effect of Zinc supplementation on the metabolic profile and expression of Nrf2, PPAR and IL-10 genes in patients undergoing Methadone Maintenance Treatment: A Randomized, Double-Blind, Placebo- Controlled Trial
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NNMT inhibition in diet-induced metabolic regulation models Source: PMC8337113 Summary: This research investigated 5-Amino-1MQ in diet-induced obese mice, measuring body weight, adipose tissue mass, and adipocyte size changes over an 11-day study period
In the HK-2 cell model transfected with KCa3.1 siRNA and cultured in a transforming growth factor-beta 1 (TGF-1) environment, as well as in the STZ-induced KCa3.1+/+and KCa3.1-/- mouse models, it was found that calcium-activated potassium channel (KCa3.1) deficiency can restore abnormal mitophagy [120]