The non-treated group was used as a control, and cell-penetrating peptide (CPP)-conjugated GHK was used as a positive control
Further research is essential to thoroughly investigate HO-1s regulatory mechanisms, its interaction with other transcription factors, and its functions across varying kinds and phases of diabetes
Methods Participants Nineteen participants with type 2 diabetes, managed by a stable dose of metformin monotherapy (5002000 mg daily for at least 3 months), were recruited from the community and provided written informed consent
But as deficiency deepens, numbness and tingling in hands and feet develop, followed by balance problems, depression, and in severe cases, irreversible nerve damage
Chi Y-H, Hsiao J-K, Lin M-H, Chang C, Lan C-H, Wu H-C
Licensing remains the primary safeguard