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Steuerman R, Shevah O, Laron Z: Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies
Des(1-3)IGF-I: a truncated form of insulin-like growth factor-I
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The only comparator for efficacy outcomes was within-patient change from baseline, with the exception of estimated improvement in near-adult height, for which a historical cohort of patients with untreated Laron syndrome 18 was used
It makes it ineffective
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