Dupr, A
(2023) 'The Rationale for Vitamin, Mineral, and Cofactor Treatment in the Precision Medical Care of Autism Spectrum Disorder', *Biomolecules*, 13(2), p
204,207 These results raise the possibility that RNAP II and mtRNAPs might function as both sensors and executors, which sense NAD + /NADH ratios and induce the NAD + capping to regulate the gene expression, leading to the crosstalk between cellular NAD + metabolism and transcriptional activity
Preclinical models demonstrate that these compounds reduce reactive oxygen species, stabilize mitochondrial membrane potential, enhance mitophagy, and activate NRF2 dependent transcription, which translates into attenuation of ASD like behaviors in VPA, propionic acid, maternal immune activation, and BTBR paradigms (De Mattos et al., 2020
Functional medicine research highlights that a sluggish SUOX enzyme leads to sulfite accumulation, which directly inhibits the clearance of histamine and mimics severe histamine intolerance
GHK-Cu kann auch topisch in Serumform angewendet werden, oft zusammen mit Retinoiden oder Vitamin C
