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We do not know for certain whether getting an updated COVID-19 vaccine every year would protect people against emerging coronaviruses, but its plausible

Toll-like receptors: significance, ligands, signaling pathways, and functions in mammals

doi: 10.3390/ijms20184472 Summary Keywords Glutathione, SARS-CoV-2, COVID-19, reactive oxygen species, oxidative stress, acute respiratory distress syndrome, atherosclerosis, atherothrombosis Citation Labarrere CA and Kassab GS (2022) Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease

These effects were statistically significant versus the placebo control

Ophthalmic Res