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Therapy with a GLP-1 RA or sodium-glucose cotransporter 2 inhibitor (SGLT2 inhibitor) that has proven CV benefit is recommended for initial therapy, with or without metformin based on glycemic needs, in patients with indicators of high-risk or established CV disease

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Rats receiving BPC-157 at doses of 10 micrograms or 10 nanograms per kilogram showed improvement across every measured outcome: clinical recovery, microscopic nerve architecture, morphometric analysis, electromyography (EMG), and functional walking recovery measured by the sciatic functional index

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