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Indeed, there are multiple primary or secondary bile acid chemosensors in the liver (348, 354) or scattered along the gastrointestinal tract (355), where they ensure a direct negative feedback aiding detoxification (356) and protecting from hepatotoxicity and carcinogenicity displayed by some secondary bile salt such as lithocholic acid

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Heartburn or acid reflux can develop as stomach emptying slows

Cell 167(4):897914

Each dose increase typically brings a temporary return of side effects as the body adjusts to higher drug levels

Many teenagers with polycystic ovary syndrome have insulin resistance and high insulin levels [39]