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Imagine this clinical scenario: a long-term patient suddenly presents at your clinic complaining of a strange sensation, like tingling or burning in their mouth (oral paraesthesia), with no apparent dental cause

Material is supplied lyophilised and should be stored as stated on the batch documentation

Because results vary by individual

S(CAM- d 15 TPP) 2 , dichloride salt A solution of 5-aminopentyltripentadeuterotriphenylphosphonium bromide hydrogen bromide (102 mg, 0.2 mmol, prepared as for SS(CAM- d 15 TPP) 2 above), 2,2-thiodiacetic (15 mg, 0.1 mmol), HBTU (90 mg, 0.22 mmol) and DIPEA (0.07 mL, 0.4 mmol) in anhydrous DMF (1.0 mL) was stirred under argon for 1 h

Simultaneously, the examiner bend-grasps the ulnar side of the hand then forces it in the dorsal and palmar direction relative to the radius

The flat field correction was enabled during image acquisition, and no additional optical filters were used