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The age group of 4064 constituted the majority of incident patients over the entire period, and the least represented group overall was children and adolescents below the age of 18

Several factors may explain why some patients report flu-like symptoms when taking tirzepatide, even though these are not formally recognized adverse effects

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The identity and differential expression of the isoforms were confirmed by Western blot (Figure S2C and G) and mass spectra, suggesting that both isoforms were compatible with phosphorylation of the most acidic isoforms (Figure S2D and H)

Persistent bleeding over multiple bowel movements, bleeding that increases in volume rather than resolving, or new-onset bleeding in patients aged 45 or older should trigger urgent medical assessment

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