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These medicines include semaglutide (Ozempic, Wegovy, Rybelsus), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), and tirzepatide (Mounjaro), which is a dual GIP/GLP-1 receptor agonist rather than a pure GLP-1 agonist
Briggs GG, Ambrose PJ, Nageotte MP, et al
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2002;76(5):1158S-1161S
This comes alongside a broader surge of industrial buildout: A planned $27 billion investment to establish four new mega sites in the US A new injectables facility in Germany slated for 2027 A $1 billion expansion in Limerick, Ireland last year Additional capacity investments in India through local contractors In the most recent quarter, tirzepatide, marketed as Mounjaro and Zepbound, generated $10.1 billion in sales and has become the bestselling medicine in the world
Although these compounds are often studied within similar experimental domains, their mechanistic profiles differ
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