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There, we have to assume the dysfunction of the nitrergic pathway (for instance, excision-immediate heavy loss of endothelium cells from the vascular wall results with less NO-production ability (24)), acting differently on the damaged tissue integrity (10, 25)

Citation on PubMed Langner C, Denk H

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That more GH signaling is inherently beneficial for longevity or metabolic health

It is less concerned with "nursing sick localized cells back to health" and much more focused on building entirely new, rapid connections