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Future studies should be done prior to determining the translatability of the current work to cholangiopathies, including evaluation of NAC treatment in WT mice, evaluating NAC potential toxicity, along with further age time points of treatment and potentially optimization of NAC delivery to the EHBD

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The concentration of Human S100A12 in the samples is then determined by comparing the OD of the samples to the standard curve

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Neurobiology of Disease, 103, 89100