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Preliminary data show greater reductions in fasting glucose and HbA1c with a weekly injection

That effect belongs to GLP-1 medications like semaglutide and tirzepatide

Same drug, same receptor occupancy, different cascade output

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A pilot study investigating the metabolic impact of intensive lifestyle intervention has shown that an intensive lifestyle programme consisting of structured educational group sessions and individual appointments can achieve sustained lifestyle improvement and weight loss in people with new onset of T2D without the need for oral glucose-lowering treatments [89]