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Obesity is associated with impaired adipose tissue mitochondrial function and a reduction in circadian clock genes in adipose tissue 1,22,23

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Patients with pre-existing risk factors, such as diabetes or heart disease, may already have an elevated risk of NAION, making it difficult to determine the drugs direct role

Chen Y, Wang J, Xu D, Xiang Z, Ding J, Yang X, et al

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