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This precipitation either soaks into the soil (infiltration) where it joins groundwater , or it runs off over the landscape to join surface water in rivers, lakes, or streams
3 In B12 deficiency, methylmalonic acid (MMA) can accumulate, and it is thought that elevated MMA, alongside elevated homocysteine, contributes to damage of the myelin sheath (which protects nerve cells and speeds up nerve transmission), which can cause irreversible neurological problems
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But to keep our readers on topic, I will discuss the how-to from a post-failure perspective
After reconstitution, most laboratories aliquot the stock and keep it frozen to minimize freeze-thaw cycles that can degrade peptide integrity