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But theres also the fact that regeneration of ascorbate involves glutaredoxin, which requires the presence of glutathione as an electron donor (8)

This means that it binds to the same receptors as does endogenous ghrelin (the GHSR-1a receptors) and that it stimulates the cells in the pituitary gland to release more GH without raising ACTH or cortisol levels [3]

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10.1038/nn.3734 168 PanB.JingL.CaoM.HuY.GaoX.BuX.et al (2021)

doi: 10.3389/fmicb.2024.1354989 126 ZhangX.WuM.WangJ.ChenJ.YuW.PanH

Regarding clinical intervention strategies, ferroptosis inhibitors and antioxidants provide promising new therapeutic options for CHD management