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10.1136/annrheumdis-2014-205635 4 AngiolilliC.KabalaP

The fact that TRANSCEND produced peer-reviewed NEJM-level evidence for efficacy in this population with an 80% responder rate and a 20-percentage-point placebo-adjusted BMI swing signals that the rare disease field's investment in precision pharmacology for orphan conditions can yield results as striking as anything produced in the mass-market obesity space

CJC-1295 formulation

In the 56-week trials, approximately 10% of patients treated with SAXENDA and 4% of patients treated with placebo discontinued treatment due to an adverse reaction [see Adverse Reactions (6.1)]

By structuring eating windows and controlling calorie intake, it can help prevent weight regain

It may also benefit dental health, as low levels of coenzyme q10 have been found in pets with poor gum health