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Resveratrol protects against cognitive dysfunction and insulin resistance in T2DM by reducing extracellular vesicle- and miR-9-3p cargo-induced oxidative stress, inflammation, and ferroptosis in the ER and hippocampus [166]

ACS Nano (2022) 16:1303748

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Effects of lipoic acid on hepatic fat accumulation in rats fed high fructose diets High-carbohydrate diets are effectively converted to specific FAS in the liver via upregulation and activation of lipogenic enzymes, most notably FAS and ACC, corresponding to higher plasma TG and total FA concentrations but lower hepatic TG and total FAs [107]