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Requires careful evaluation are adults with active or historical cancer (growth-promoting compounds require oncology-history review), significant cardiovascular disease, multiple medications requiring interaction screening, or pituitary conditions for growth hormone secretagogues

doi: 10.1093/hmg/8.12.2247

Short-term treatment of NFV increases ROS generation and diminishes levels of GSH and the detoxification enzyme superoxide dismutase in a pancreatic insulinoma cell line (Vincent et al., 2004

C., Pezeshki, A., Reidelberger, R

Important considerations: The substantial weight loss is partly fat and partly lean mass, so resistance training and adequate protein intake are important to preserve muscle

Patients should prepare to: Have regular checkups to tweak doses or monitor side effects