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Recommended dose: 1 capsule per day to complete a main meal

Bonkowski MS, Sinclair DA

Because of this short half-life, most clinical protocols call for daily dosing or, in some cases, twice-daily dosing to maintain consistent levels in the body throughout the treatment period

35,36 A final note: An elevated temperature in dogs can be a result of fever (associated with infection or inflammation) or can be due to hyperthermia (an elevated temperature due to activity, anxiety, excitement, or overexposure to a hot environment)

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and hence, interfered with the enzyme inhibition assessment monitor via tyrosinase activity using the spectrophotometric method 104