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Targeting PI3K/mTOR pathways has shown promise in preclinical trials, with omipalisib being well-tolerated in IPF subjects [148, 149]

Mild sleep restriction: Initially restricts the amount of time spent in bed to reduce nighttime awakenings, then slowly increases the duration while maintaining sleep quality

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The -subunit (Kv1.1) exhibits the oxidoreductase activity and contains the NADPH-binding site, which is thought to be the sensor of intracellular redox potential that in turn regulates the channel [95]

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