This phenomenon can be reversed by BCAA diet restriction or regulating the BCKDK/PPM1K ratio in mouse models of obesity and insulin resistance
Huang J, Chen G, Wang J, Liu S, Su J
The B vitamins help to support glutathione metabolism and therefore combat this increased oxidative stress leading to a reduction in menopausal symptoms
doi: 10.1002/alz.12154, 56
Zeng HY, Zhu XA, Zhang C et al (2005) Identification of sequential events and factors associated with microglial activation, migration, and cytotoxicity in retinal degeneration in rd mice
The fat-free mass (equation [14]) should be considered rather than total body weight for obese patients, and correction should be made for muscle wasting in severely ill patients