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It furthermore provides a detailed overview of current clinical experience with pharmacologic activators of HIF signalling as a novel comprehensive and physiologic approach to the treatment of anaemia

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These findings imply that NRF2 is of great importance for maintaining iron/heme homeostasis [99, 104]

Calabrese and Mehendale, 1996

Another trial randomised older adults to healthy eating, hypocaloric diet, or very-low energy diet (VLED) groups, found that all diets improved cardiometabolic risk markers and reduced the number of people requiring T2D and CVD prevention medication, especially with VLEDs [62]