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1 Introduction According to global cancer statistics 2022, gastric cancer (GC) ranks fifth in terms of incidence and mortality, seriously threatening human health ( In comparison to supportive therapy alone, combined chemotherapy can improve both survival rates and quality of life for patients with advanced or metastatic disease

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Once the reduced form of glutathione (GSH) undergoes various oxidation reactions in the body, GSH is converted into glutathione disulfide or GSSG, the oxidized form of glutathione

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