Consult the manufacturers instructions for choice of vehicle, appropriate dilution or volume for dissolving the drugs to be injected, including the route and rate of injection
Later, after B12 stores are back to normal, they may prescribe high doses of oral B12 replacement
It does this by scavenging reactive oxygen species (ROS), which helps protect mitochondrial components such as proteins, lipids, and DNA from oxidative damage, thereby preserving mitochondrial function
This can reduce side effects while maintaining or improving efficacy a principle well-established in pharmacology
The mechanism is remarkably similar across diseases
The ankles constant weight-bearing demands further complicate matters, as complete rest remains impractical for most people