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Phase Titration Dose 75 mg Frequency 1-3x weekly Notes Increase by ~25 mg if assessment phase is well tolerated

Ethical approval All animal-related procedures were conducted in accordance with the institutional ethical guidelines for the care and use of laboratory animals, following approval from the Institutional Animal Ethics Committee (IAEC) of Banasthali Vidyapith, Rajasthan, under approval number BV/IAEC/September2023/10

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