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The mechanism is specific and brutal: hypothalamic damage reduces production of alpha-melanocyte-stimulating hormone (-MSH), a neuropeptide that under normal conditions activates the melanocortin-4 receptor (MC4R)

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He has a calm demeanor and takes the time to listen to his patients concerns, allowing him to build strong relationships which result in optimal care

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However small human studies suggest that yerba mate or green mate (the same active compound) can be helpful for fat loss and appetite reduction