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Seven membrane-bound NOX catalytic isoforms, referred to as NOX1 to NOX5, dual oxidase 1 (DUOX1), and 2 (DUOX2) have been identified with similar but distinct structural and subcellular localization characteristics

Participants were not allowed to have been diagnosed or to have manifested symptoms for more than a total of three years

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Features persistent redness plus acne-like papules (red bumps) and pustules (pus-filled spots)