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It is indicated for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) as characterized by low sexual desire that causes marked distress or interpersonal difficulty and is NOT due to: References Mechanism of Action 1-2 Bremelanotide, a MCR agonist, non-selectively works on several receptor subtypes MC1R-MC5R in the central nervous system

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Sermorelin activates the GHRH receptor (GHRH-R), a class B GPCR using cAMP signaling

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