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Proton Pump Inhibitors These medications reduce stomach acid production

By extrapolation from the established profiles of approved GLP-1 receptor agonists including semaglutide (Wegovy SmPC, MHRA/EMC) and tirzepatide (Mounjaro SmPC, MHRA/EMC) clinicians should anticipate the need to review and potentially reduce antihypertensive doses as significant weight loss occurs, in line with BNF and NICE guidance principles

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Diabetic medicine: a journal of the British Diabetic Association

Huffman says the relationship is often misunderstood

This can affect the central nervous system and lead to depression