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3.3 Changes in serum cobalamin by supplementation route and dosage Across 35 comparisons, the mean percentage increase in serum cobalamin following supplementation was approximately 293%, confirming the overall effectiveness of vitamin B12 interventions (Supplementary Table S4)

However, at this stage, we do not yet have sufficient high-quality human data to fully understand the safety, efficacy, and long-term effects of BPC-157

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