These synthetic peptides differ in amino acid sequence and biologic properties.I3 In our previous studies, we demonstrated that injection of thymosin a', thymopentin, or THF-y2 into aging mice can increase T-cell functions when spleen cells were tested in vitro for T helper cell activity, proliferative responses to T-cell mitogens, cytokine production, and expression of cytokine receptors
Studies have shown that adding n-3 LCPUFA to TB treatment regimens reduced M.tb burden [50], decreased systemic and lung inflammation [51], and enhanced weight in M.tb -infected C3HeB/FeJ mice with a sufficient n-3 LCPUFA status [52]
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