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To date, few radiosensitising drugs have been approved for use clinically ( in vitro and ex vivo models of oesophageal adenocarcinoma ( Metformin is a clinically approved drug used for the management of type II diabetes ( This study demonstrates, through real-time live cell metabolic profiling and transcriptomic profiling, that metformin significantly alters energy metabolism in both in vitro and ex vivo models of rectal adenocarcinoma and importantly, radiosensitises radioresistant rectal cancer cells to clinically-relevant doses of X-ray radiation

Science 340 , 626630 (2013)

We focus on organic and wild-crafted sourcing whenever possible and avoid GMOs and synthetic additives

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This low absorption rate occurs because NAC undergoes extensive first-pass metabolism

However, these findings do not yet form one complete and fully confirmed mechanism