For injections, both medications are designed to be self-administered under the skin (in the abdomen, thigh, or upper arm)
Wegovy Pill (Oral Semaglutide 25 mg Daily) According to the FDA approval announcement dated December 22, 2025, the Wegovy pill is indicated for the same population as the injection formulation
Youll start with a low oral Wegovy dose and work your way up If youre new to treatment with Wegovy, youll follow a specific dosage schedule when starting Wegovy pills
Diarrhea and constipation: Both common, sometimes alternating
Allodynia and tirzepatide: is it a class effect The question of whether allodynia is specific to semaglutide or a broader GLP-1 receptor agonist class effect has significant implications for treatment decisions
Therefore, it is recommended to use contraception while using this medicine, the patient information leaflet for Wegovy states