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Clinical Points Glucagon-like peptide-1 (GLP-1) agonists can reduce motivation to seek alcohol and prevent a relapse of alcohol use disorder in a dose-dependent manner

doi: 10.1038/npp.2017.150, 113 PhelanS

The albumin binding acts as a time-release mechanism, maintaining consistent blood levels between injections

And beyond that, should incretin therapies really be dosed in such a standardized way

Intramuscular injection of tirzepatide is not dangerous, but it can cause more pain, faster absorption, and potentially more intense side effects including increased muscle soreness

If you experience leg cramps while taking semaglutide, make sure to stay hydrated, maintain electrolyte balance, and talk to your healthcare provider for further advice