Numerous reviews and meta-analyses have established associations between genetic variants in Vitamin D 3 -related genes and diabetes susceptibility
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They evaluated the role of LSD1 in VDR-mediated gene transcription for Cdkn1a, E2f1, Cyp24a1, and S100g using CWR22 cells transplanted in athymic nude mice via qRT-PCR-TaqMan
A metabolome analysis disclosed that sulphasalazine triggers an increase in the glutamate-derived TCA cycle intermediate -ketoglutarate in addition to a decrease in cysteine and glutathione